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How does the human body attack the West Nile Virus?
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Default How does the human body attack the West Nile Virus? - 12-15-2008, 06:39 AM

Also, what are the capsid and noncapsid proteins in the West Nile Virus?Is there a cure for West Nile Virus? ------
   
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Default 12-15-2008, 08:01 AM

The body has IgM to attack the virus.The capsid is an arrangement of 60 protomers in a tightly packed Icosahedral structure. Each protomer consists of 4 polypeptides known as VP (viral protein)1, 2, 3 and 4. All of these VP polypeptides originate form one protomer known as VP0 that is cleaved to give the different capsid components. The Icosahedral is said to have a triangulation number of 3, this means that in the icosahedral structure each of the 60 triangles that make up the capsid are slip into 3 little triangles with a subunit on the corner. (en.wikipedia.org)Your body is the only cure against virus. ------
   
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Default 12-15-2008, 03:47 PM

Actually the first answer has it mostly right.West Nile virus is a flavivirus, meaning it is shaped like a icosehedron. The capsid proteins form a shell around the viral RNA (see picture below, sorry the site is in spanish). The non capsid proteins are all the other proteins that the virus makes which aren't part of the shell structureAs far as I know there is no human vaccine for WNV (although there is a horse vaccine), and there is no cure for WNV outside of your bodies own immune response. ------
   
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