[fail r us]

When it comes to drugs, people tend to point to acetaminophen (Tylenol) as the most destructive to the liver. Is it really more destructive than other substances? How much would an adult have to take in order to cause irreparable damage to his or her liver?Obviously, this is body mass specific, so please specify the limit and the weight of the person with that limit.The bottle usually says to take two tablets, which I believe are 500 mg each. This, however, is probably safe for a 100 lb granny.Just to clarify: what is the healthy dose for an average young person?

[isthatu?]

4 with alcohol on an empty stomach

[SWH]

everybody's different. don't take any drugs, if possible.

[kds6107]

The max dose of Tylenol is 4g per day (4000mg)Stay under that and she should be fine. Tylenol is one of the safest drugs for elderly people. It's not really body mass specific because it doesn't distribute into the fat. However I wouldn't start on a dose of 4 grams per day on a person who is obviously frail.

[sunflower]

Generally, 4000mg per 24 hours for acute use or 2000mg per 24 hours with chronic use. Other sources say 3200mg per 24 hours. There are many other hepatotoxic drugs, but acetaminophen is available without prescription and is so commonly used that its hepatotoxicity is well known. Combining it with other hepatotoxic substances (e.g. alcohol) increases the risk of liver damage.

Although I cannot give a specific, technical answer to your question, I can give you general guidelines.While like with most medicines there is some dependence of dosing based on weight, for Tylenol it is not a major factor and so weight is rarely taken into account when determining dosage. Generally, many hospitals try not to give more than 4 g of Tylenol in a 24 hr period. Sometimes they do go beyond this and for a period of days otherwise healthy, young individuals can take 6 or 7 g without series liver problems, but beyond that things start to get damaged. These signs of liver trouble are usually subtle though and frequently there are no indications of toxicity except for a rise in various enzymes used to measure liver health.Now as far as"irreparable"liver damage is concerned, well generally the problem with Tylenol ingestion, as far as I know, is not so much irreparable liver damage, as the liver is a rather stout organ and can handle its share of abuse, but instead acute liver failure which can result in death. It doesn't really matter, though, because I cannot recall the toxic dosages for either occurrence and so can't answer either question. (Sorry!) As I stated above, however, while your body based on health and size can probably take a fair some of pills, most hospitals rarely go above 4 g/day for any patient if they can help it.