01-08-2009, 09:48 PM
Hi dear ,There are currently eight known types of Human Herpesvirus:Herpes simplex type IHerpes simplex type IIVaricella-zoster virus (VZV/HHV-3)Epstein-Barr virus (EBV/HHV-4)Cytomegalovirus (CMV/HHV-5)Human herpesvirus type 6 (HBLV/HHV-6)Human herpesvirus type 7 (HHV-7)Kaposi's sarcoma herpesvirus (KSHV/HHV-8Herpes simplex virus types I and II (HHV1&2)Primary infection occurs through a break in the mucus membranes of the mouth or throat, via the eye or genitals or directly via minor abrasions in the skin. Because of the universal distribution of the virus, most individuals are infected by 1-2 years of age; initial infection is usually asymptomatic, although there may be minor local vesicular lesions. Local multiplication is followed by viraemia and systemic infection; and subsequent life-long latent infection with periodic reactivation.Systemic infection, eg fever, sore throat, and lymphadenopathy may pass unnoticed. If immunocompromised it may be life-threatening with fever, lymphadenopathy, pneumonitis, and hepatitis.Gingivostomatitis: Ulcers filled with yellow slough appear in the mouth.Herpetic whitlow: A breach in the skin allows the virus to enter the finger, causing a vesicle to form. Often affects childrens'nurses.Traumatic herpes (herpes gladiatorum): Vesicles develop at any site where HSV is ground into the skin by brute force.Eczema herpeticum: HSV infection of eczematous skin; usually children.Herpes simplex meningitis: This is uncommon and usually self-limiting (typically HSV II in women during a primary attack) - see meningitis.Genital herpes: Usually HSV type 2 See genital herpes simplexHSV keratitis: Corneal dendritic ulcers. Avoid steroids.Herpes Simplex Encephalitis: Usually HSV type1. Spreads centripetally, eg from cranial nerve ganglia, to frontal and temporal lobes. Suspect if fever, fits, headaches, odd behaviour, dysphasia, hemiparesis, or coma or subacute brainstem encephalitis, meningitis, or myelitis; see HSV Encephalitisfeel free to ask
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